Smad3 as a mediator of the fibrotic response
نویسندگان
چکیده
منابع مشابه
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Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases.
Fibrosis is a pathological process characterized by massive deposition of extracellular matrix (ECM) such as type I/III collagens and fibronectin that are secreted by an expanded pool of myofibroblasts, which are phenotypically altered fibroblasts with more contractile, proliferative, migratory and secretory activities. Fibrosis occurs in various organs including the lung, heart, liver and kidn...
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ژورنال
عنوان ژورنال: International Journal of Experimental Pathology
سال: 2004
ISSN: 0959-9673
DOI: 10.1111/j.0959-9673.2004.00377.x